Ace the CDCA OSCE Challenge 2025 – Master Your Clinical Skills with Confidence!

The presence of two flat, brown lesions on the skin and face of a 27-year-old is indicative of Kaposi sarcoma, particularly when considering the demographic context and the characteristics of the lesions. Kaposi sarcoma is a type of cancer that often presents as lesions on the skin, which can appear as flat, brown, or purplish spots. These lesions are associated with the proliferation of blood vessels and are characteristic of the disease, especially in immunocompromised individuals, such as those with HIV/AIDS.

The other conditions do not typically present in this manner. Neurofibromatosis, for instance, is characterized by café-au-lait spots and neurofibromas, which differ in appearance and presentation from flat brown lesions. HIV positivity can lead to various skin manifestations, but the lesions described are more specific to Kaposi sarcoma. Meanwhile, a hematoma typically results from trauma and would appear differently, often presenting as a raised, discolored area due to bleeding under the skin rather than as a flat lesion.

Thus, evaluating the appearance and context of the lesions points towards Kaposi sarcoma as the most fitting diagnosis.